CGBVS予測モデル(Ion Channel)

予測モデルを選択:

相互作用(リガンド)データ数 ◎:500~、○:100~499、△:1~99、x:0

UniProt ID Accession Number Protein Name Model
ChEMBL22 ChEMBL25
5HT3A_HUMAN P46098 5-hydroxytryptamine receptor 3A
5HT3B_HUMAN O95264 5-hydroxytryptamine receptor 3B
5HT3C_HUMAN Q8WXA8 5-hydroxytryptamine receptor 3C
5HT3D_HUMAN Q70Z44 5-hydroxytryptamine receptor 3D
5HT3E_HUMAN A5X5Y0 5-hydroxytryptamine receptor 3E
ABCC8_HUMAN Q09428 ATP-binding cassette sub-family C member 8 ×
ABCC9_HUMAN O60706 ATP-binding cassette sub-family C member 9 ×
ACH10_HUMAN Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10
ACHA_HUMAN P02708 Acetylcholine receptor subunit alpha
ACHA2_HUMAN Q15822 Neuronal acetylcholine receptor subunit alpha-2
ACHA3_HUMAN P32297 Neuronal acetylcholine receptor subunit alpha-3
ACHA4_HUMAN P43681 Neuronal acetylcholine receptor subunit alpha-4
ACHA5_HUMAN P30532 Neuronal acetylcholine receptor subunit alpha-5
ACHA6_HUMAN Q15825 Neuronal acetylcholine receptor subunit alpha-6
ACHA7_HUMAN P36544 Neuronal acetylcholine receptor subunit alpha-7
ACHA9_HUMAN Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9
ACHB_HUMAN P11230 Acetylcholine receptor subunit beta
ACHB2_HUMAN P17787 Neuronal acetylcholine receptor subunit beta-2
ACHB3_HUMAN Q05901 Neuronal acetylcholine receptor subunit beta-3
ACHB4_HUMAN P30926 Neuronal acetylcholine receptor subunit beta-4
ACHD_HUMAN Q07001 Acetylcholine receptor subunit delta
ACHE_HUMAN Q04844 Acetylcholine receptor subunit epsilon
ACHG_HUMAN P07510 Acetylcholine receptor subunit gamma
ANO1_HUMAN Q5XXA6 Anoctamin-1
ANO2_HUMAN Q9NQ90 Anoctamin-2 ×
ASIC1_HUMAN P78348 Acid-sensing ion channel 1
ASIC3_HUMAN Q9UHC3 Acid-sensing ion channel 3
CA2D1_HUMAN P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1
CA2D2_HUMAN Q9NY47 Voltage-dependent calcium channel subunit alpha-2/delta-2
CA2D3_HUMAN Q8IZS8 Voltage-dependent calcium channel subunit alpha-2/delta-3 ×
CA2D4_HUMAN Q7Z3S7 Voltage-dependent calcium channel subunit alpha-2/delta-4 ×
CAC1A_HUMAN O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A
CAC1B_HUMAN Q00975 Voltage-dependent N-type calcium channel subunit alpha-1B
CAC1C_HUMAN Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C
CAC1D_HUMAN Q01668 Voltage-dependent L-type calcium channel subunit alpha-1D
CAC1E_HUMAN Q15878 Voltage-dependent R-type calcium channel subunit alpha-1E ×
CAC1F_HUMAN O60840 Voltage-dependent L-type calcium channel subunit alpha-1F
CAC1G_HUMAN O43497 Voltage-dependent T-type calcium channel subunit alpha-1G
CAC1H_HUMAN O95180 Voltage-dependent T-type calcium channel subunit alpha-1H
CAC1I_HUMAN Q9P0X4 Voltage-dependent T-type calcium channel subunit alpha-1I
CAC1S_HUMAN Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S
CACB1_HUMAN Q02641 Voltage-dependent L-type calcium channel subunit beta-1 ×
CACB2_HUMAN Q08289 Voltage-dependent L-type calcium channel subunit beta-2 ×
CACB3_HUMAN P54284 Voltage-dependent L-type calcium channel subunit beta-3 ×
CACB4_HUMAN O00305 Voltage-dependent L-type calcium channel subunit beta-4 ×
CCG1_HUMAN Q06432 Voltage-dependent calcium channel gamma-1 subunit ×
CCG2_HUMAN Q9Y698 Voltage-dependent calcium channel gamma-2 subunit ×
CCG3_HUMAN O60359 Voltage-dependent calcium channel gamma-3 subunit ×
CCG4_HUMAN Q9UBN1 Voltage-dependent calcium channel gamma-4 subunit ×
CCG5_HUMAN Q9UF02 Voltage-dependent calcium channel gamma-5 subunit ×
CCG6_HUMAN Q9BXT2 Voltage-dependent calcium channel gamma-6 subunit ×
CCG7_HUMAN P62955 Voltage-dependent calcium channel gamma-7 subunit ×
CCG8_HUMAN Q8WXS5 Voltage-dependent calcium channel gamma-8 subunit ×
CFTR_HUMAN P13569 Cystic fibrosis transmembrane conductance regulator
CRCM1_HUMAN Q96D31 Calcium release-activated calcium channel protein 1
CTSR1_HUMAN Q8NEC5 Cation channel sperm-associated protein 1 ×
CY24B_HUMAN P04839 Cytochrome b-245 heavy chain
GBRA1_HUMAN P14867 Gamma-aminobutyric acid receptor subunit alpha-1
GBRA2_HUMAN P47869 Gamma-aminobutyric acid receptor subunit alpha-2
GBRA3_HUMAN P34903 Gamma-aminobutyric acid receptor subunit alpha-3
GBRA4_HUMAN P48169 Gamma-aminobutyric acid receptor subunit alpha-4
GBRA5_HUMAN P31644 Gamma-aminobutyric acid receptor subunit alpha-5
GBRA6_HUMAN Q16445 Gamma-aminobutyric acid receptor subunit alpha-6
GBRB1_HUMAN P18505 Gamma-aminobutyric acid receptor subunit beta-1
GBRB2_HUMAN P47870 Gamma-aminobutyric acid receptor subunit beta-2
GBRB3_HUMAN P28472 Gamma-aminobutyric acid receptor subunit beta-3
GBRD_HUMAN O14764 Gamma-aminobutyric acid receptor subunit delta
GBRE_HUMAN P78334 Gamma-aminobutyric acid receptor subunit epsilon
GBRG1_HUMAN Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1
GBRG2_HUMAN P18507 Gamma-aminobutyric acid receptor subunit gamma-2
GBRG3_HUMAN Q99928 Gamma-aminobutyric acid receptor subunit gamma-3
GBRP_HUMAN O00591 Gamma-aminobutyric acid receptor subunit pi
GBRR1_HUMAN P24046 Gamma-aminobutyric acid receptor subunit rho-1
GBRR2_HUMAN P28476 Gamma-aminobutyric acid receptor subunit rho-2
GBRR3_HUMAN A8MPY1 Gamma-aminobutyric acid receptor subunit rho-3
GBRT_HUMAN Q9UN88 Gamma-aminobutyric acid receptor subunit theta
GLRA1_HUMAN P23415 Glycine receptor subunit alpha-1
GLRA2_HUMAN P23416 Glycine receptor subunit alpha-2
GLRA3_HUMAN O75311 Glycine receptor subunit alpha-3
GLRB_HUMAN P48167 Glycine receptor subunit beta ×
GRIA1_HUMAN P42261 Glutamate receptor 1
GRIA2_HUMAN P42262 Glutamate receptor 2
GRIA3_HUMAN P42263 Glutamate receptor 3
GRIA4_HUMAN P48058 Glutamate receptor 4
GRIK1_HUMAN P39086 Glutamate receptor ionotropic, kainate 1
GRIK2_HUMAN Q13002 Glutamate receptor ionotropic, kainate 2
GRIK3_HUMAN Q13003 Glutamate receptor ionotropic, kainate 3
GRIK4_HUMAN Q16099 Glutamate receptor ionotropic, kainate 4
GRIK5_HUMAN Q16478 Glutamate receptor ionotropic, kainate 5
HCN1_HUMAN O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
HCN2_HUMAN Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
HCN3_HUMAN Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
HCN4_HUMAN Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
ITPR1_HUMAN Q14643 Inositol 1,4,5-trisphosphate receptor type 1
ITPR2_HUMAN Q14571 Inositol 1,4,5-trisphosphate receptor type 2
ITPR3_HUMAN Q14573 Inositol 1,4,5-trisphosphate receptor type 3
KCAB1_HUMAN Q14722 Voltage-gated potassium channel subunit beta-1 ×
KCJ11_HUMAN Q14654 ATP-sensitive inward rectifier potassium channel 11
KCMA1_HUMAN Q12791 Calcium-activated potassium channel subunit alpha-1
KCNA1_HUMAN Q09470 Potassium voltage-gated channel subfamily A member 1
KCNA2_HUMAN P16389 Potassium voltage-gated channel subfamily A member 2
KCNA3_HUMAN P22001 Potassium voltage-gated channel subfamily A member 3
KCNA4_HUMAN P22459 Potassium voltage-gated channel subfamily A member 4
KCNA5_HUMAN P22460 Potassium voltage-gated channel subfamily A member 5
KCNA7_HUMAN Q96RP8 Potassium voltage-gated channel subfamily A member 7 ×
KCNB1_HUMAN Q14721 Potassium voltage-gated channel subfamily B member 1
KCNB2_HUMAN Q92953 Potassium voltage-gated channel subfamily B member 2
KCNC1_HUMAN P48547 Potassium voltage-gated channel subfamily C member 1
KCND2_HUMAN Q9NZV8 Potassium voltage-gated channel subfamily D member 2 ×
KCND3_HUMAN Q9UK17 Potassium voltage-gated channel subfamily D member 3
KCNE1_HUMAN P15382 Potassium voltage-gated channel subfamily E member 1
KCNH2_HUMAN Q12809 Potassium voltage-gated channel subfamily H member 2
KCNH3_HUMAN Q9ULD8 Potassium voltage-gated channel subfamily H member 3 ×
KCNJ1_HUMAN P48048 ATP-sensitive inward rectifier potassium channel 1
KCNJ3_HUMAN P48549 G protein-activated inward rectifier potassium channel 1
KCNJ4_HUMAN P48050 Inward rectifier potassium channel 4
KCNJ5_HUMAN P48544 G protein-activated inward rectifier potassium channel 4
KCNJ6_HUMAN P48051 G protein-activated inward rectifier potassium channel 2
KCNJ8_HUMAN Q15842 ATP-sensitive inward rectifier potassium channel 8
KCNK2_HUMAN O95069 Potassium channel subfamily K member 2
KCNK3_HUMAN O14649 Potassium channel subfamily K member 3
KCNK4_HUMAN Q9NYG8 Potassium channel subfamily K member 4 ×
KCNK9_HUMAN Q9NPC2 Potassium channel subfamily K member 9
KCNKA_HUMAN P57789 Potassium channel subfamily K member 10 ×
KCNKI_HUMAN Q7Z418 Potassium channel subfamily K member 18 ×
KCNN1_HUMAN Q92952 Small conductance calcium-activated potassium channel protein 1
KCNN2_HUMAN Q9H2S1 Small conductance calcium-activated potassium channel protein 2
KCNN3_HUMAN Q9UGI6 Small conductance calcium-activated potassium channel protein 3
KCNN4_HUMAN O15554 Intermediate conductance calcium-activated potassium channel 4
KCNQ1_HUMAN P51787 Potassium voltage-gated channel subfamily KQT member 1
KCNQ2_HUMAN O43526 Potassium voltage-gated channel subfamily KQT member 2
KCNQ3_HUMAN O43525 Potassium voltage-gated channel subfamily KQT member 3
KCNQ4_HUMAN P56696 Potassium voltage-gated channel subfamily KQT member 4
KCNQ5_HUMAN Q9NR82 Potassium voltage-gated channel subfamily KQT member 5
MCLN3_HUMAN Q8TDD5 Mucolipin-3
NMD3A_HUMAN Q8TCU5 Glutamate receptor ionotropic, NMDA 3A
NMD3B_HUMAN O60391 Glutamate receptor ionotropic, NMDA 3B
NMDE1_HUMAN Q12879 Glutamate receptor ionotropic, NMDA 2A
NMDE2_HUMAN Q13224 Glutamate receptor ionotropic, NMDA 2B
NMDE3_HUMAN Q14957 Glutamate receptor ionotropic, NMDA 2C
NMDE4_HUMAN O15399 Glutamate receptor ionotropic, NMDA 2D
NMDZ1_HUMAN Q05586 Glutamate receptor ionotropic, NMDA 1
NOX1_HUMAN Q9Y5S8 NADPH oxidase 1
NOX5_HUMAN Q96PH1 NADPH oxidase 5
P2RX1_HUMAN P51575 P2X purinoceptor 1
P2RX2_HUMAN Q9UBL9 P2X purinoceptor 2
P2RX3_HUMAN P56373 P2X purinoceptor 3
P2RX4_HUMAN Q99571 P2X purinoceptor 4
P2RX6_HUMAN O15547 P2X purinoceptor 6
P2RX7_HUMAN Q99572 P2X purinoceptor 7
PERF_HUMAN P14222 Perforin-1 ×
PKD2_HUMAN Q13563 Polycystin-2 ×
RYR1_HUMAN P21817 Ryanodine receptor 1
RYR2_HUMAN Q92736 Ryanodine receptor 2 ×
SCN1A_HUMAN P35498 Sodium channel protein type 1 subunit alpha
SCN2A_HUMAN Q99250 Sodium channel protein type 2 subunit alpha
SCN3A_HUMAN Q9NY46 Sodium channel protein type 3 subunit alpha
SCN4A_HUMAN P35499 Sodium channel protein type 4 subunit alpha
SCN5A_HUMAN Q14524 Sodium channel protein type 5 subunit alpha
SCN7A_HUMAN Q01118 Sodium channel protein type 7 subunit alpha
SCN8A_HUMAN Q9UQD0 Sodium channel protein type 8 subunit alpha
SCN9A_HUMAN Q15858 Sodium channel protein type 9 subunit alpha
SCNAA_HUMAN Q9Y5Y9 Sodium channel protein type 10 subunit alpha
SCNBA_HUMAN Q9UI33 Sodium channel protein type 11 subunit alpha
SCNNA_HUMAN P37088 Amiloride-sensitive sodium channel subunit alpha
TRPA1_HUMAN O75762 Transient receptor potential cation channel subfamily A member 1
TRPC3_HUMAN Q13507 Short transient receptor potential channel 3
TRPC5_HUMAN Q9UL62 Short transient receptor potential channel 5 ×
TRPC6_HUMAN Q9Y210 Short transient receptor potential channel 6
TRPC7_HUMAN Q9HCX4 Short transient receptor potential channel 7 ×
TRPM2_HUMAN O94759 Transient receptor potential cation channel subfamily M member 2
TRPM5_HUMAN Q9NZQ8 Transient receptor potential cation channel subfamily M member 5 ×
TRPM6_HUMAN Q9BX84 Transient receptor potential cation channel subfamily M member 6
TRPM8_HUMAN Q7Z2W7 Transient receptor potential cation channel subfamily M member 8
TRPV1_HUMAN Q8NER1 Transient receptor potential cation channel subfamily V member 1
TRPV3_HUMAN Q8NET8 Transient receptor potential cation channel subfamily V member 3
TRPV4_HUMAN Q9HBA0 Transient receptor potential cation channel subfamily V member 4
VDAC2_HUMAN P45880 Voltage-dependent anion-selective channel protein 2 ×
Total target proteins: 147 175

2020年3月公開