{"id":2835,"date":"2026-02-25T09:00:00","date_gmt":"2026-02-25T00:00:00","guid":{"rendered":"https:\/\/www.insilico.jp\/blog\/?p=2835"},"modified":"2026-02-24T15:43:56","modified_gmt":"2026-02-24T06:43:56","slug":"cgas-sting_nucleocytosis","status":"publish","type":"post","link":"https:\/\/www.insilico.jp\/blog\/2026\/02\/25\/cgas-sting_nucleocytosis\/","title":{"rendered":"\u3010\u8ad6\u6587\u63b2\u8f09\u3011cGAS-IFN-I responses by extracting nuclear DNA from dying cells via nucleocytosis"},"content":{"rendered":"\n<p>\u63b2\u8f09\u8a8c : Nature Communications  (2026) 17:1658<\/p>\n\n\n\n<p>\u8ad6\u6587\u30bf\u30a4\u30c8\u30eb : cGAS-IFN-I responses by extracting nuclear DNA from dying cells via nucleocytosis<\/p>\n\n\n\n<p>\u8457\u8005 : Hideo Negishi, Yusuke Wada, Yoshitaka Shirasaki, Tomoya Hayashi, Yuji Kubota, Tomio Iwasaki, Mina Kurosawa, Tatsuma Ban, Daisuke Muto, Yusuke Suenaga, Taichi Kojima, Yuzuki Matsuda, Sean Lord Irish, Kosuke Dodo, Toru Suzuki, Mai Yamagishi, Burcu Temizoz, <strong>Atsushi Yoshimori, Chisato Kanai<\/strong>, Yoji Nagasaki, Masaki Ohmuraya, Tomohiko Tamura, Atsushi Iwama, Toshifumi Inada, Etsushi Kuroda, Kouji Kobiyama, Noriko Toyama-Sorimachi, Mutsuhiro Takekawa, Cevayir Coban &amp; Ken J. Ishii<\/p>\n\n\n\n<p>DOI :\u00a0<a href=\"https:\/\/doi.org\/10.1038\/s41467-026-68839-w\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1038\/s41467-026-68839-w<\/a><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u63b2\u8f09\u8a8c : Nature Communications (2026) 17:1658 \u8ad6\u6587\u30bf\u30a4\u30c8\u30eb : cGAS-IFN-I responses by extracting nuclear DNA from dying &#8230;<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[118,34,10],"tags":[136,137,138,139,135],"class_list":["post-2835","post","type-post","status-publish","format-standard","hentry","category-ai-drug-discovery","category-announcements","category-ligandscout","tag-cgas-sting","tag-nucleocytosis","tag-pca","tag-pharmacophore-screening","tag-self-dna"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.3.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u3010\u8ad6\u6587\u63b2\u8f09\u3011cGAS-IFN-I responses by extracting nuclear DNA from dying cells via nucleocytosis - 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